06241862 is referenced by 431 patents and cites 24 patents.

An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis is made using a non-conductive integrated reagent/blood separation layer containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The integrated layer formulation is printed over a conductive carbon element to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity and hydrophilicity such that one drying it forms a two-dimensional network on the surface of the conductive element. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.

Title
Disposable test strips with integrated reagent/blood separation layer
Application Number
9/228855
Publication Number
6241862 (B1)
Application Date
January 12, 1999
Publication Date
June 5, 2001
Inventor
Oliver W H Davies
Inverness
US
David Scott
Witney Oxon
US
Elliot V Plotkin
Inverness
US
Geoff Hall
Inverness
US
Manuel Alvarez Icaza
Inverness
US
Jerome F McAleer
Wantage
US
Agent
Oppedahl & Larson
US
Assignee
Inverness Medical Technology
MA, US
IPC
G01N 27/26
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