06238686 is referenced by 95 patents and cites 109 patents.

Anti-microbial coatings and method of forming same on medical devices are provided. The coatings are formed by depositing a biocompatible metal by vapour deposition techniques to produce atomic disorder in the coating such that a sustained release of metal ions sufficient to produce an anti-microbial effect is achieved. Preferred deposition conditions to achieve atomic disorder include a lower than normal substrate temperature, and one or more of a higher than normal working gas pressure and lower than normal angle of incidence of coating flux. Anti-microbial powders formed by mechanical working to produce atomic disorder are also provided. The invention extends to other metal coating and powders similarly formed so as to provide enhanced solubility.

Title
Anti-microbial coating for medical devices
Application Number
8/882286
Publication Number
6238686 (B1)
Application Date
June 25, 1997
Publication Date
May 29, 2001
Inventor
Larry Roy Morris
Edmonton
US
Robert Edward Burrell
Sherwood Park
US
Agent
Finnegan Henderson Farabow Garrett & Dunner L
US
Assignee
Westaim Technologies
US
IPC
A61F 2/02
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