06235000 is referenced by 170 patents and cites 63 patents.

Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other interventional and diagnostic catheters.

Title
Apparatus for crossing total occlusion in blood vessels
Application Number
9/440308
Publication Number
6235000 (B1)
Application Date
November 17, 1999
Publication Date
May 22, 2001
Inventor
Ronald G French
Palo Alto
CA, US
Fred H Co
Santa Clara
CA, US
Richard E Hill
Berkeley
CA, US
Matthew R Selmon
Woodside
CA, US
Charles F Milo
Union City
CA, US
Agent
Wilson Sonsini Goodrich and Rosati
US
Assignee
LuMend
CA, US
IPC
A61M 5/178
View Original Source