06219577 is referenced by 337 patents and cites 45 patents.

Catheter-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the wall tissues of tubular compartments of the living body. One catheter device provides an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only. Another device uses iontophoresis only, electroporation only, or combined iontophoresis and electroporation. In the latter device, the two procedures may be applied sequentially in any order without removing or repositioning the catheter.

Title
Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
Application Number
9/253272
Publication Number
6219577 (B1)
Application Date
February 19, 1999
Publication Date
April 17, 2001
Inventor
Steven Freear
Leeds
US
Neville Crawford
Wetherby
US
Charles L Brown III
Atlanta
GA, US
Agent
Sutherland Asbill & Brennan
US
Assignee
Global Vascular Concepts
GA, US
IPC
A61N 1/30
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