06217527 is referenced by 281 patents and cites 63 patents.

Methods and apparatus for crossing totally to substantially occluded blood vessels by passing a redirectable wire such as a guidewire from a relatively proximal point past the occlusion within a subintimal space formed between the intimal layer and the adventitial layer of a blood vessel wall. The wire may be advanced to a point distal to the occlusion, and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. The deflecting catheter may include a flapper valve assembly or preformed actuator wire for redirecting the guidewire. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn, and the guidewire may be available for introduction of other interventional and diagnostic catheters for performing procedures such as stenting.

Title
Methods and apparatus for crossing vascular occlusions
Application Number
9/163854
Publication Number
6217527 (B1)
Application Date
September 30, 1998
Publication Date
April 17, 2001
Inventor
Amiel Aguilar
Palo Alto
CA, US
Ronald French
Palo Alto
CA, US
Mark Campello
Millbrae
CA, US
Fred Co
Santa Clara
CA, US
Charles F Milo
San Mateo
CA, US
Matthew R Selmon
Atherton
CA, US
Agent
Wilson Sonsini Goodrich & Rosati
US
Assignee
LuMend
CA, US
IPC
A61B 5/00
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