06214368 is referenced by 126 patents and cites 66 patents.

The present invention provides a novel process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provides both bioactivity and structural integrity. This novel amorphous material can be reacted with other calcium phosphates at or below 37° C. to form a bone-like material consisting of poorly crystalline hydroxyapatite.

Title
Bone substitution material and a method of its manufacture
Application Number
8/650764
Publication Number
6214368 (B1)
Application Date
May 20, 1996
Publication Date
April 10, 2001
Inventor
Maria Aiolova
Brookline
MA, US
Christian Rey
Castanet
US
Dosuk D Lee
Brookline
MA, US
Agent
Clark & Elbing
US
Agent
Mary Rose Scozzafava
US
Assignee
Etex Corporation
MA, US
IPC
A61K 9/16
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