A self-centering blood clot filter is provided. The filter includes an anchoring portion including a generally cylindrical radially expandable body including an axial lumen extending therethrough. The filter further includes a filtering portion including a conical body concentrically aligned within the axial lumen of the anchoring portion. The conical body of the filtering portion is tapered to form a distal tip. As such, the blood clot filter can be properly centered within the lumen of a vessel for effective lysing of blood clots.