06197325 is referenced by 232 patents and cites 82 patents.

This invention provides methods for the localized delivery of supplemented tissue sealants, wherein the supplemented tissue sealants comprise at least one composition which is selected from one or more antibodies, analgesics, anticoagulants, anti-inflammatory compounds, antimicrobial compositions, antiproliferatives, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like. Further provided are methods of using the site-specific supplemented tissue sealants, including preparation of a biomaterial.

Title
Supplemented and unsupplemented tissue sealants, methods of their production and use
Application Number
8/474084
Publication Number
6197325 (B1)
Application Date
June 7, 1995
Publication Date
March 6, 2001
Inventor
Christian Haudenschild
Rockville
MD, US
Gene Liau
Darnestown
MD, US
Carlos I Lasa Jr
Quezon
US
William Nash Drohan
Springfield
VA, US
Martin James MacPhee
Gaithersburg
MD, US
Agent
Sterne Kessler Goldstein & Fox P L L C
US
Assignee
The American National Red Cross
DC, US
IPC
A61K 35/14
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