06174291 is referenced by 251 patents and cites 80 patents.

A system characterizes tissue using fluorescence spectroscopy, such as light-induced fluorescence. Native fluorescence (“autofluorescence”) from endogenous tissue without requiring fluorescence-enhancing agents is used to distinguish between normal tissue, hyperplastic tissue, adenomatous tissue, and adenocarcinomas. The system provides endoscopic image enhancement for easy location of a tissue site for optical biopsy tissue characterization. The system allows the use of an integrated endoscopic diagnosis and treatment device for immediate diagnosis and treatment without interchanging equipment and relocating the tissue site. The system is also integrated with existing endoscopy equipment for initiating and displaying the diagnosis. The system provides an adjunctive tool to histopathological tissue classification or, alternatively, further treatment is based on the optical biopsy system diagnosis itself.

Title
Optical biopsy system and methods for tissue diagnosis
Application Number
9/37722
Publication Number
6174291 (B1)
Application Date
March 9, 1998
Publication Date
January 16, 2001
Inventor
David R Walsh
River Falls
WI, US
John G Yager
Bloomington
MN, US
Robert A Palme
Taylor Falls
MN, US
Ronald R Zimmermann
Robbinsdale
MN, US
Scott R Wilson
Maple Grove
MN, US
Chester E Sievert Jr
Mahtomedi
MN, US
Brain T McMahon
Minnetonka
MN, US
Agent
Schwegman Lundberg Woessner & Kluth P A
US
Assignee
SpectraScience
MN, US
IPC
A61B 10/00
View Original Source