06153651 cites 13 patents.

Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them.

Ortho-substituted benzoylguanidines of the formula I ##STR1## in which R(1) to R(4) have the meanings given in the claims, are suitable, as antiarrhythmic pharmaceuticals having a cardioprotective component, for the prophylaxis and treatment of infarction and for the treatment of angina pectoris. They also inhibit, in a preventive manner, the pathophysiological processes associated with the genesis of ischemically induced damage, in particular associated with the triggering of ischemically induced cardiac arrhythmias.

Title
Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them
Application Number
8/808295
Publication Number
6153651
Application Date
February 28, 1997
Publication Date
November 28, 2000
Inventor
Andreas Weichert
Egelsbach
DE
Jan Robert Schwark
Frankfurt
DE
Wolfgang Scholz
Eschborn
DE
Hans Jochen Lang
Hofheim
DE
Heinz Werner Kleemann
Bischofsheim
DE
Joachim Brendel
Bad Vilbel
DE
Udo Albus
Florstadt
DE
Agent
Finnegan Henderson Farabow Garrett and Dunner L
Assignee
Hoechst Aktiengesellschaft
DE
IPC
C07C 233/64
A61K 31/165
View Original Source