06139819 is referenced by 103 patents and cites 312 patents.

Novel contrast agents which may be used for diagnostic and therapeutic use. The compositions may comprise a lipid, a protein, polymer and/or surfactant, and a gas, in combination with a targeting ligand. In preferred embodiments, the targeting ligand targets coagula, including emboli and/or thrombi, particularly in patients suffering from an arrhythmic disorder. The contrast media can be used in conjunction with diagnostic imaging, such as ultrasound, as well as therapeutic applications, such as therapeutic ultrasound.

Title
Targeted contrast agents for diagnostic and therapeutic use
Application Number
666129
Publication Number
6139819
Application Date
September 17, 1997
Publication Date
October 31, 2000
Inventor
Edward W Gertz
Paradise Valley
AZ, US
Thomas A Fritz
Tucson
AZ, US
Evan C Unger
Tucson
AZ, US
Agent
Woodcock Washburn Kurtz Mackiewicz & Norris
Assignee
ImaRx Pharmaceutical
AZ, US
IPC
A61K 9/127
A61B 8/00
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