06139578 is referenced by 180 patents and cites 72 patents.

The present invention provides a synthetic, poorly-crystalline apatitic (PCA) calcium phosphate material seeded with cells. Preferably, the cells are tissue-forming or tissue-degrading cells. The compositions provided by the present invention are useful for a variety of applications, including in vivo and in vitro tissue growth (preferably bone or cartilage), osseous augmentation, and methods of diagnosing disease states by assaying tissue-forming potential of cells isolated from a host. The invention also provides in vitro cell culture systems and cell encapsulation matrices.

Title
Preparation of cell seeded ceramic compositions
Application Number
446182
Publication Number
6139578
Application Date
February 13, 1998
Publication Date
October 31, 2000
Inventor
Maria Aiolova
Brookline
MA, US
Christian Rey
Castanet
FR
Dosuk D Lee
Brookline
MA, US
Agent
Clark & Elbing
Agent
Mary Rose Scozzafava
Assignee
Etex Corporation
MA, US
IPC
A61F 2/02
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