06136187 is referenced by 34 patents and cites 25 patents.

A mixture of chromatographic particles and a solution of water, alcohol and metal alkoxide may be injected by means of a syringe into a capillary column as a gel. The volatile components in the gel are evaporated by means of heating and gas pressure reduction to form a porous sol-gel glass matrix attached to the inner wall of the separation channel. The pores are large enough for the passage of protons, neutral and ionic species but are too small to permit significant leaching of the chromatographic particles. The separation column so formed requires no frits to maintain the glass matrix in place in the column. Electrical potential difference and/or pressure difference may be applied to cause fluid flow in the separation column to cause electrophoretic and chromatographic separation.

Title
Separation column containing porous matrix and method of packing column
Application Number
8/987287
Publication Number
6136187
Application Date
December 9, 1997
Publication Date
October 24, 2000
Inventor
Rajan P Kulkarni
Loma Linda
CA, US
Maria T Dulay
Sunnyvale
CA, US
Richard N Zare
Stanford
CA, US
Agent
Majestic Parsons Siebert & Hsue P C
Assignee
The Board of Trustees of the Leland Stanford Junior University
CA, US
IPC
B01D 15/08
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