06130200 is referenced by 112 patents and cites 66 patents.

Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 or less for systemic applications and systems releasing 10% or less of the total dose of beneficial agent in the first 24 hours after implantation for local applications. The compositions include a biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.

Title
Gel composition and methods
Application Number
8/993208
Publication Number
6130200
Application Date
December 18, 1997
Publication Date
October 10, 2000
Inventor
Theodore Tao Ian Shen
Redwood City
CA, US
Ann T Gaynor Duarte
Oakland
CA, US
Kevin J Brodbeck
Palo Alto
CA, US
Agent
Steven F Stone
John A Dhuey
Assignee
Alza Corporation
CA, US
IPC
A61K 9/16
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