06101265 is referenced by 211 patents and cites 10 patents.

An apparatus and method acquires and stores multiple resolution images from a specimen on a support and provides to the user a low magnification, reconstructed macro image of the entire specimen, or a large portion thereof, to aid the person in selecting points of interest to be viewed or analyzed at higher magnifications and resolution. The reconstructed image is formed of a large number of tiled, stored images which are coordinated and assembled to form the macro image of the specimen which is displayed on a monitor. Preferably, the stored, reconstructed image is reduced further in size by a software system before it is displayed to the user. The display may be on a local monitor over a local area network or sent over the Internet to the user who is typically a pathologist. The user selects by a marker such as a cursor the defined area of interest or region and then views higher magnification images or has them analyzed. Preferably, the pathologist can scroll to shift digitized, adjacent image tiles into view on the monitor. A fully computer-controlled microscope is used to acquire and store the digitized images and the illustrated microscope can be remotely controlled to change objective lenses, focus, light intensity, filters, field diaphragm, and to shift the microscope stage by a controller.

Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope
Application Number
Publication Number
Application Date
March 3, 1997
Publication Date
August 8, 2000
James W Bacus
James V Bacus
Downers Grove
Fitch Even Tabin & Flannery
Bacus Research Laboratories
G06F 15/00
View Original Source