06090406 is referenced by 40 patents and cites 45 patents.

A high integrity liposome comprising at least one stabile lipid and at least one peptide-like therapeutic agent associated with said liposome, adapted for parenteral administration to an animal, including a human, and method according to manufacture and use. Immunizing dosage forms comprising a liposome and an immunogen, wherein said liposome and immunogen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt according to an organic acid derivative of a sterol and an immunogen wherein said organic acid derivative of a sterol and immunogen are present in an immunization dose, and method according to use is disclosed. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristoylphosphatidylcholine (DMPC)/cholesterol liposomes, optionally in an aluminum hydroxide gel, and an immunogen wherein said DMPC/cholesterol and immunogen are present in an immunization dose, and method according to use.

Title
Potentiation of immune responses with liposomal adjuvants
Application Number
236702
Publication Number
6090406
Application Date
February 26, 1990
Publication Date
July 18, 2000
Inventor
Carl R Alving
Bethesda
MD, US
Lynn D Keyes
Upton
MA, US
Leonard Estis
Upton
MA, US
Andrew S Janoff
Yardley
PA, US
Marie S Recine
Hamilton Township
NJ, US
Alan L Weiner
Lawrenceville
NJ, US
Mircea C Popescu
Plainsboro
NJ, US
Agent
Rosanne Goodman
Kenneth B Rubin
Assignee
The Liposome Company
NJ, US
IPC
A61K 43/00
View Original Source