06086562 is referenced by 253 patents and cites 24 patents.

An automatic injection device includes a drug-filled vessel having a flexible membrane over a first opening thereof and a puncturable seal in a wall thereof, a hollow needle attached at a first end to the flexible membrane and having a sharp end positioned proximate the puncturable seal housing. A pressure source such as a combustible propellant provides a compressed gas above the flexible membrane to force the membrane into the drug-filled vessel, forcing the hollow needle through the puncturable seal and the drug contained in the vessel through the hollow needle. After the drug has been substantially evacuated from the vessel, the membrane is allowed to return to its pre-expanded state thus retracting the hollow needle into the vessel. Preferably, the flexible membrane is an elastomeric material having a plurality of concentrically configured corrugations to allow expansion of the membrane into the vessel. The inner surface of the vessel may have a dome-like shape such that expansion of the membrane into the vessel substantially matches the dome-like shape and thus forces substantially the entire amount of the drug from the vessel.

Title
Disposable automatic injection device
Application Number
797295
Publication Number
6086562
Application Date
October 1, 1998
Publication Date
July 11, 2000
Inventor
Tomasz J Petelenz
Salt Lake City
UT, US
Aaron M Best
West Jordan
UT, US
Stephen C Jacobsen
Salt Lake City
UT, US
Agent
Thorpe North & Western
Assignee
Sarcos
UT, US
IPC
A61M 05/20
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