06083524 is referenced by 78 patents and cites 249 patents.

Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers are preferably polymerized using free radical initiators under the influence of long wavelength ultraviolet light or visible light excitation. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. The macromers can be used to encapsulate cells, deliver prophylactic, therapeutic or diagnostic agents in a controlled manner, plug leaks in tissue, prevent adhesion formation after surgical procedures, temporarily protect or separate tissue surfaces, and adhere or seal tissues together.

Title
Polymerizable biodegradable polymers including carbonate or dioxanone linkages
Application Number
710689
Publication Number
6083524
Application Date
October 6, 1997
Publication Date
July 4, 2000
Inventor
Shikha P Barman
Bedford
MA, US
Luis Z Avila
Arlington
MA, US
Michelle D Powell
Tewksbury
MA, US
Ronald S Rudowsky
Sudbury
MA, US
Arthur J Coury
Boston
MA, US
Peter K Jarrett
Sudbury
MA, US
Douglas Weaver
Bedford
MA, US
Fei Yao
North Andover
MA, US
William C Nason
Westford
MA, US
Stephen D Goodrich
Woburn
MA, US
David J Enscore
Sudbury
MA, US
Amarpreet S Sawhney
Bedford
MA, US
Agent
Arnall Golden & Gregory
Assignee
Focal
MA, US
IPC
A61K 31/74
A61R 2/02
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