06076015 is referenced by 381 patents and cites 43 patents.

A cardiac rhythm management (CRM) device detects transthoracic impedance, extracts ventilation or other information, and adjusts a delivery rate of the CRM therapy accordingly. A four-phase sequence of alternating direction current pulse stimuli is periodically delivered to a patient's thorax. A transthoracic impedance signal is extracted using a weighted demodulation. Signal processing extracts ventilation information and removes cardiac stroke information using an adaptive lowpass filter. The adaptive filter cutoff frequency is based on the patient's heart rate; a higher cutoff frequency is provided for higher heart rates. Peak/valley detection indicates tidal volume, which is integrated to extract minute ventilation (MV). Short and long term averages are formed and compared to establish a MV indicated rate. Rate adjustment ignores MV information when a noise-measurement exceeds a threshold. An interference avoidance circuit delays delivery of the stimuli when telemetry pulses or other interfering signals are detected.

Title
Rate adaptive cardiac rhythm management device using transthoracic impedance
Application Number
9/32731
Publication Number
6076015
Application Date
February 27, 1998
Publication Date
June 13, 2000
Inventor
James P Nelson
Shoreview
MN, US
Steven D Check
Eden Prairie
MN, US
Scott A Reedstrom
Vadnais Heights
MN, US
Nicholas J Stessman
Minneapolis
MN, US
Marc H Cohen
Baltimore
MD, US
Jesse W Hartley
Lino Lakes
MN, US
Agent
Schwegman Lundberg Woessner and Kluth
Assignee
Cardiac Pacemakers
MN, US
IPC
A61B 5/04
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