06074688 is referenced by 49 patents and cites 40 patents.

Method for electrostatically depositing select doses of medicament powder at select locations on a substrate. Specifically, the apparatus contains a charged particle emitter for generating charged particles that charge a predefined region of a substrate and a charge accumulation control circuit for computing the amount of charge accumulated upon the substrate and deactivating the emitter when a selected quantity of charge has accumulated. Additionally, a triboelectric charging apparatus charges the medicament powder and forms a charged medicament cloud proximate the charged region of the substrate. The medicament particles within the medicament cloud electrostatically adhere to the charged region. The quantity of charge accumulated on the substrate at the predefined region and the charge-to-mass ratio of the medicament powder in the cloud control the amount (dose) of medicament deposited and retained by the substrate. Consequently, this apparatus accurately controls both medicament dosage and deposition location. Furthermore, since the substrate can be of any dielectric material that retains an electrostatic charge, the apparatus can be used to deposit medicament on substrates that are presently used in oral medicament consumption, e.g., substrates that are used to fabricate suppositories, inhalants, tablets, capsules and the like.

Title
Method for electrostatically depositing a medicament powder upon predefined regions of a substrate
Application Number
471889
Publication Number
6074688
Application Date
October 18, 1996
Publication Date
June 13, 2000
Inventor
Randall Eugene McCoy
McConnellsburg
PA, US
Christopher Just Poux
Mercerville
NJ, US
Pabitra Datta
Cranbury
NJ, US
Timothy Allen Pletcher
Eastampton
NJ, US
Agent
Dechert Price & Rhoads
Assignee
Delsys Pharmaceautical Corporation
NJ, US
IPC
B05D 3/14
B05D 1/06
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