A pipe mounting clamp comprises a generally C-shaped piece of plastic or other resilient material which is sufficiently flexible to allow a pipe to be snapped into a central pipe receiving cavity thereof while firmly retaining the same. The C-shaped member has a pair or orthogonal bores for receiving nails, screws or other fasteners which attach the C-shaped member to a stud or joist. The bores are positioned to permit the C-shaped member to be attached to a stud or joist in the appropriate orientation best suited for receiving and retaining the pipe. The bores may be formed of a plurality of offset slots that open onto opposite sides of the C-shaped member to allow the clamp to be injection molded without mold parts that move. The central pipe receiving cavity may be formed with a plurality of radially inwardly directed pipe engaging ribs.