06073759 is referenced by 56 patents and cites 17 patents.

A unit dose, gas-filled syringe is provided which is filled with gas and packaged in a gas barrier material prior to use to increase shelf-life, that is, to minimize gas leakage and dilution of the contents of the syringe. The syringe is filled with a selected gas and sealed inside a container made from a high gas barrier material. The container is also filled with the selected gas. The container material is selected to have a gas transmission rate sufficient to prevent the selected gas from diffusing out of the container into the atmosphere. The volume of gas in the container is greater that atmospheric pressure to prevent atmospheric contaminants from entering the container and syringe.

Title
Pre-filled package containing unit dose of medical gas and method of making same
Application Number
838824
Publication Number
6073759
Application Date
February 22, 1999
Publication Date
June 13, 2000
Inventor
Eugene de Juan Jr
Phoenix
MD, US
Andrew N Lamborne
Denver
CO, US
Agent
Peter F Dike Bronstein Roberts & Cushman Corless
Assignee
Johns Hopkins University
MD, US
IPC
A61M 31/00
B65D 81/20
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