06045755 is referenced by 115 patents and cites 59 patents.

In a first embodiment, this invention includes an integrated robot apparatus for performing combinatorial chemistry synthesis protocols and having interchangeable work-stations, robot arm tools, and reaction vessels and reaction vessel arrays. The work-stations and tools are specialized to perform tasks necessary for the synthesis in a plurality of the reaction vessels grouped in a plurality of the reaction vessel arrays. Preferably, these elements function interchangeably because they have standardized sizes and conformation. The work-stations and tools include those for fluid dispensing or aspirating from individual reaction vessels or from all the reaction vessels in an array simultaneously. The reaction vessels can include, alternatively, stackable, ball-sealed reaction vessels, microtitre-like reaction vessel arrays, arrays of independent reaction vessels, valve-sealed reaction vessels, septum-sealed reaction vessels, and syringe reaction vessels. In alternative embodiments, this invention includes these work-stations, tools, reaction vessels and reaction vessel arrays in various combinations or sub-combinations either for use in partially integrated robots or for manual or standalone use.

Title
Apparatus and method for combinatorial chemistry synthesis
Application Number
8/815975
Publication Number
6045755
Application Date
March 10, 1997
Publication Date
April 4, 2000
Inventor
Viktor Krchnak
San Diego
CA, US
Vit Pokorny
Prague
CZ
Michael Lebl
San Diego
CA, US
Agent
Pennie & Edmonds
Assignee
Trega Biosciences
CA, US
IPC
B01L 3/14
F16K 3/02
B01J 19/00
G01N 35/00
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