06033427 is referenced by 473 patents and cites 23 patents.

The present invention relates to a device for percutaneously sealing of an internal puncture site comprising a tissue portion having a puncture formed therethrough. A locating device is mounted for longitudinal movement relative to a guide wire towards and away from the puncture site. Delivery structure has a distal end portion and is mounted for longitudinal movement relative to the guide wire. A tubular puncture site engaging member has a distal end portion and is mounted exteriorly of the delivery structure for longitudinal movement relative to the guide wire. A supply of fluid thrombogenic material which will be capable of promoting clotting when delivered to the puncture site is provided. The delivery structure has a fluid passageway open to the distal end portion thereof and communicated to the supply of fluid thrombogenic material. The locating device and the puncture site engaging member are positioned with respect to one another such that they can be moved together towards the puncture site. The locating device transmits a signal to the user indicating that the distal end portion of the puncture site engaging member is engaged with the tissue portion in surrounding relation with respect to the puncture. The distal end portion of the delivery structure can be positioned adjacent the puncture site and the fluid thrombogenic material can then be delivered from the supply to the puncture site through the fluid passageway. The puncture site engaging member is constructed and arranged such that the distal end portion thereof will surround the fluid thrombogenic material being delivered to the puncture site so as to prevent the material from flowing away from the puncture site when the distal end portion of the puncture site engaging member is engaged with the tissue portion in surrounding relation with respect to the puncture, thereby allowing the material to promote clotting and seal the puncture. The present invention also relates to a method for percutaneously sealing internal punctures sites and to a sealing device having improved locating device for properly positioning the device with respect to the puncture site. Further, the present invention is well-suited for application to arterial puncture sites.

Title
Method and device for percutaneous sealing of internal puncture sites
Application Number
9/226717
Publication Number
6033427
Application Date
January 7, 1999
Publication Date
March 7, 2000
Inventor
Benjamin I Lee
4911 Van Ness St. NW., Washington, 20016
DC, US
Agent
Pillsbury Madison & Sutro
IPC
A61B 17/00
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