06013188 is referenced by 99 patents and cites 18 patents.

A method of qualitative analysis of microscopic biological specimens is disclosed in which the specimens are rendered magnetically responsive by immunosspecific binding with feuromagnetic colloid. The specimens are placed in a vessel having a feuromagnetic capture structure supported on a transparent wall. The vessel is then placed in a magnetic field for inducing a high gradient region in the vicinity of the capture structure and, in particular, adjacent to the capture structure along the direction of the applied field. The magnetically responsive specimens are collected and immobilized by the high gradient along the wall adjacent to the capture structure for unobstructed microscopic observation. Subpapulations of distinct types of cells can thus be observed and differentiated. As transport force, such as gravity or an externally applied magnetic gradient, may be applied to the vessel to move the specimens into the high gradient region.

Title
Methods for biological substance analysis employing internal magnetic gradients separation and an externally-applied transport force
Application Number
8/867233
Publication Number
6013188
Application Date
June 2, 1997
Publication Date
January 11, 2000
Inventor
Paul A Liberti
Huntingdon
PA, US
Leon W M M Terstappen
Huntingdon
PA, US
Agent
Dann Dorfman Herrell and Skillman
Assignee
Immunivest Corporation
DE, US
IPC
G01N 33/533
B01D 35/06
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