05981180 is referenced by 357 patents and cites 67 patents.

A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry. Flow cytometric measurements are used to classify, in real-time, beads within an exposed beadset and textual explanations, based on the accumulated data obtained during real-time analysis, are generated for the user. The inventive technology enables the simultaneous, and automated, detection and interpretation of multiple biomolecules or DNA sequences in real-time while also reducing the cost of performing diagnostic and genetic assays.

Title
Multiplexed analysis of clinical specimens apparatus and methods
Application Number
8/540814
Publication Number
5981180
Application Date
October 11, 1995
Publication Date
November 9, 1999
Inventor
Mark B Chandler
Austin
TX, US
R Jerrold Fulton
Cedar Hill
TX, US
Van S Chandler
Dallas
TX, US
Agent
Gilberto M Pepper Hamilton Villacorta
Assignee
Luminex Corporation
TX, US
IPC
C12Q 1/68
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