05968965 is referenced by 29 patents and cites 24 patents.

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

Title
Inhibitors of farnesyl-protein transferase
Application Number
8/786516
Publication Number
5968965
Application Date
January 21, 1997
Publication Date
October 19, 1999
Inventor
George D Hartman
Lansdale
PA, US
Christopher J Dinsmore
North Wales
PA, US
Agent
Mark R Daniel
David A Muthard
Dianne Pecoraro
Assignee
Merck & Co
NJ, US
IPC
C07D 233/64
A61K 31/415
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