05965433 is referenced by 93 patents and cites 15 patents.

A portable perfusion/oxygenation module includes respiratory gas driven dual positive displacement pumps coupled to a stacked membrane oxygenator unit for perfusion fluid oxygenation, a valving manifold to control perfusate flow-direction coupled to an organ chamber designed to enable easy installation of organ and maintenance of intra and extra organ fluid pressure. All of the components and oxygen cylinders are fitted into an insulated chest capable of sustaining perfusion and oxygenation for 24 hours. The perfusion/oxygenation apparatus requires no electrical power, is compact with the total weight including the perfusion fluids and organ weighing less than 50 pounds. With low cumulative weight and the extremely low flow rate of gas required to pump the perfusate, the oxygen supply is capable of sustaining pumping operation for 24 hours without gas cylinder change. The dual pumps have axially aligned, commonly connected pistons using adjustable linkages that provide a simple and robust means of adjusting perfusate volume and pumping rate. No movable membranes, diaphragms or electrical power are required to deliver oxygenated perfusate.

Title
Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
Application Number
8/652696
Publication Number
5965433
Application Date
May 29, 1996
Publication Date
October 12, 1999
Inventor
James L Matthews
Dallas
TX, US
John K Heacox
Mesquite
TX, US
William W Gardetto
Bedford
TX, US
Agent
James L Mayor Day Caldwell and Keeton L Jackson
Assignee
Trans D A T A Service
TX, US
IPC
C12M 3/00
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