05942241 is referenced by 156 patents and cites 122 patents.

A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible local anesthesia when implanted or injected in a patient, and a pharmaceutically acceptable, i.e., non-toxic, non-glucocorticoid augmenting agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without the augmenting agent.

Title
Formulations and methods for providing prolonged local anesthesia
Application Number
8/793861
Publication Number
5942241
Application Date
June 16, 1997
Publication Date
August 24, 1999
Inventor
Joseph Tigner
New Milford
CT, US
Paul Goldenheim
Wilton
CT, US
Ronald M Burch
Wilton
CT, US
Richard Sackler
Greenwich
CT, US
Mark Chasin
Manalapan
NJ, US
Agent
Davidson Davidson & Kappel
Assignee
Euro Celtique
LU
IPC
A61K 9/22
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