05916588 is referenced by 32 patents and cites 44 patents.

A high integrity liposome comprising at least one stabile lipid and at least one peptide-like therapeutic agent associated with the liposome, adapted for parenteral administration to an animal, including a human, and method according to manufacture and use.

Immunizing dosage forms comprising a liposome and an immunogen, wherein the liposome and immunogen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt according to an organic acid derivative of a sterol and an immunogen are present in an immunization dose, and method according to uses is disclosed. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristolyphosphatidylcholine (DMPC)/cholesterol liposomes, optionally in an aluminum hydroxide gel, and an immunogen wherein the DMPC/cholesterol and immunogen are present in an immunization dose, and method according to use.

Title
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
Application Number
599691
Publication Number
5916588
Application Date
May 25, 1995
Publication Date
June 29, 1999
Inventor
Carl R Alving
Bethesda
MD, US
Lynn D Keyes
Upton
MA, US
Leonard Estis
Upton
MA, US
Andrew S Janoff
Yardley
PA, US
Marie S Recine
Hamilton Township
NJ, US
Alan L Weiner
Lawrenceville
NJ, US
Mircea C Popescu
Plainsboro
NJ, US
Agent
Rosanne Goodman
Kenneth Rubin
Assignee
The Liposome Company
NJ, US
IPC
A61K 43/00
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