05900481 is referenced by 323 patents and cites 9 patents.

Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are described. As compared to "flat" surfaces, beads linked to a solid support provide an increased surface area for immobilization of nucleic acids. Furthermore, by selecting a bead with the desired functionality, a practitioner can select a functionalization chemistry for immobilizing nucleic acids, which is different from the chemistry of the solid support.

Title
Bead linkers for immobilizing nucleic acids to solid supports
Application Number
8/746036
Publication Number
5900481
Application Date
November 6, 1996
Publication Date
May 4, 1999
Inventor
Hubert Koster
Concord
MA, US
David M Lough
Hamburg
DE
Agent
Foley Hoag & Eliot
Agent
Beth E Arnold
Assignee
Sequenom
CA, US
IPC
C07H 33/18
C07H 21/04
C07H 1/00
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