05874082 is referenced by 54 patents and cites 16 patents.

Methods for preventing or treating an antibody-mediated disease in patient are presented, the methods comprising administration of a humanized monoclonal antibody or fragment thereof that is capable of binding to a human CD40 antigen located on the surface of a human B cell, wherein the binding of the antibody to the CD40 antigen prevents the growth or differentiation of the B cell. Humanized monoclonal antibodies and fragments useful in these methods are also presented.

Title
Humanized anti-CD40 monoclonal antibodies and fragments capable of blocking B cell proliferation
Application Number
910222
Publication Number
5874082
Application Date
February 23, 1996
Publication Date
February 23, 1999
Inventor
Mark de Boer
Heemskerk
NL
Agent
Robert P Blackburn
Paul B Savereide
Donald J Pochopien
Assignee
Chiron Corporation
CA, US
IPC
C07K 16/28
A61K 39/395
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