05855866 is referenced by 190 patents and cites 23 patents.

The present invention relates generally to methods and compositions for targeting the vasculature of solid tumors using immunologically-based reagents. In particular aspects, antibodies carrying diagnostic or therapeutic agents are targeted to the vasculature of solid tumor masses through recognition of tumor vasculature-associated antigens, such as, for example, through endoglin binding, or through the specific induction of endothelial cell surface antigens on vascular endothelial cells in solid tumors.

Title
Methods for treating the vasculature of solid tumors
Application Number
846349
Publication Number
5855866
Application Date
March 2, 1994
Publication Date
January 5, 1999
Inventor
Francis J Burrows
Dallas
TX, US
Philip E Thorpe
Dallas
TX, US
Agent
Arnold White & Durkee
Assignee
Board of Regenis The University of Texas System
TX, US
IPC
A61K 39/395
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