05840746 is referenced by 33 patents and cites 28 patents.

The present invention provides a method of treating a neurodegenerative disease and in particular Alzheimers disease which comprises administering to a human in need thereof a therapeutically effective amount of a non-steroid COX-II inhibitor. Although a wide range of COX-II inhibitors may be employed but it is preferred to employ compounds of the Formula I: ##STR1##

Title
Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
Application Number
82196
Publication Number
5840746
Application Date
September 5, 1997
Publication Date
November 24, 1998
Inventor
Michel Therien
Dollard Des Ormeaux
CA
Serge Leger
Dollard Des Ormeaux
CA
Zhaoyin Wang
Pierrefonds
CA
Yves Leblanc
Kirkland
CA
Petpiboon Prasit
Kirkland
CA
Jacques Yves Gauthier
Laval
CA
Yves Ducharme
Montreal
CA
Agent
David L Rose
Curtis C Panzer
Assignee
Merck Frosst Canada
CA
IPC
A61K 31/27
A61K 31/34
A61K 31/425
A61K 31/38
View Original Source