05827216 is referenced by 271 patents and cites 35 patents.

A pericardiocentesis apparatus and method for accessing the pericardial space. The invention consists of inserting a percutaneous tube whose tip has a hole which is positioned over and contacts the anterior pericardium. Introducing a vacuum within the tube forms a pericardial bleb within that hole. A guided needle within the tube is advanced to puncture the pericardial bleb while avoiding contact with the epicardium. A hollow filament or electrocardial lead or flexible guide wire within the needle can then be advanced into said pericardial cavity. The guide wire may be used to guide a intrapericardial catheter into the pericardial space for injection or infusion of selected therapeutic agents into the pericardial space to treat various heart and blood vessel diseases. Controlled drug release material(s) can be injected through the needle for the slow and/or sustained delivery of the therapeutic agents into the pericardial cavity.

Title
Method and apparatus for accessing the pericardial space
Application Number
8/484299
Publication Number
5827216
Application Date
June 7, 1995
Publication Date
October 27, 1998
Inventor
Ruben Trono
Marion
OH, US
James W Meador
Houston
TX, US
Stephen R Igo
Clear Lake Shores
TX, US
Agent
Tim L Burgess
Assignee
Cormedics
TX, US
IPC
A61N 1/30
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