05825488 is referenced by 191 patents and cites 11 patents.

A method and an apparatus for determining analytical data concerning the inside of a scattering matrix, in particular of a biological sample. In a detection step detection measurements are carried out in which light is irradiated into the matrix as primary light at an irradiation site (12) through an interface bounding the scattering matrix (6) and light emerging out of the scattering matrix through the interface is detected as secondary light at a detection site (13) at a predetermined measuring distance from the irradiation site, in order to determine as a measurement variable a measurable physical property of the light which varies due to the interaction of the light with the scattering matrix, which measurement variable is a measure of the analytical data to be determined. In an evaluation step the analytical data are determined on the basis of the measurement variable measured in the detection step. In order that such a matrix analysis may be carried out with relatively simple measuring means, at least two detection measurements are carried out in the detection step with different reflection conditions at the interface (5) between the irradiation site (12) and the detection site (13), in each of which the measurement value of the measurement variable is determined.

Title
Method and apparatus for determining analytical data concerning the inside of a scattering matrix
Application Number
8/745204
Publication Number
5825488
Application Date
November 8, 1996
Publication Date
October 20, 1998
Inventor
Dirk Boecker
Heidelberg
DE
Matthias Essenpreis
Gauting
DE
Mark Cope
Avon
GB
Matthias Kohl
London
GB
Agent
Nikaido Marmelstein Murray & Oram
Assignee
Boehringer Mannheim
DE
IPC
G01N 21/47
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