05820551 is referenced by 552 patents and cites 43 patents.

A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; a first conductor and a second conductor each extend along the support and comprise means for connection to the circuitry. An active electrode, positioned to contact the liquid mixture and the first conductor, comprises a single layer deposit of an enzyme capable of catalyzing a reaction involving the compound, a conductive material and an electron mediator, capable of transferring electrons between the enzyme-catalyzed reaction and the first conductor. A reference electrode is positioned to contact the mixture and the second conductor. The system includes circuitry adapted to provide an electrical signal representative of the current. The two-electrode strip is manufactured, e.g., by screen printing an admixture of an enzyme, a conductive material, and a mediator as a single layer onto the substrate.

Strip electrode with screen printing
Application Number
Publication Number
Application Date
June 6, 1995
Publication Date
October 13, 1998
Graham Davis
1504 Fox Run Dr., Plainsborough, 08536
James Michael McCann
4 Ash Grove, Headington, Oxford
Irving John Higgins
Cotswold, Graze Hill, Ravensden, Bedford MK44 2TM
Hugh Allen Oliver Hill
Nine Clover Close, Oxford OX2 9JH
A61B 5/05
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