05811119 is referenced by 33 patents and cites 36 patents.

A reduced-toxicity formulation of carotenoids is disclosed which is stable in an aqueous environment. The formulation includes a carotenoid, lipid carrier particles (such as liposomes), and an intercalation promoter agent (such as a triglyceride), which causes the carotenoid to be substantially uniformly distributed with the lipid in the lipid carrier particles. The molar ratio of carotenoid to lipid is greater than about 1:10. Also disclosed is a method of inhibiting the growth of cancer cells, which comprises administering to a living subject a therapeutically effective amount of a composition as described above.

Title
Formulation and use of carotenoids in treatment of cancer
Application Number
51890
Publication Number
5811119
Application Date
October 22, 1996
Publication Date
September 22, 1998
Inventor
Alan C Hayman deceased
late of Houston
TX, US
Robert P Lenk
Willis
TX, US
Gabriel Lopez Berestein
Houston
TX, US
Roman Perez Soler
Houston
TX, US
Kapil Mehta
Houston
TX, US
Agent
Arnold White & Durkee
Assignee
Aronex Pharmaceuticals
TX, US
Board of Regents the University of Texas
TX, US
IPC
A61K 9/127
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