05798340 is referenced by 47 patents and cites 51 patents.

Nucleotide analogs characterized by the presence of an amidate lirked amino acid or an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise a phosphoamidate or ester bond that is hydrolysed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for the synthesis and use are described.

Title
Nucleotide analogs
Application Number
123483
Publication Number
5798340
Application Date
May 6, 1996
Publication Date
August 25, 1998
Inventor
William A Lee
Los Altos
CA, US
Ernest J Prisbe
Los Altos
CA, US
Michael S Louie
San Mateo
CA, US
Murty N Arimilli
Fremont
CA, US
Robert J Jones
Millbrae
CA, US
Norbert W Bischofberger
San Carlos
CA, US
Agent
Daryl D Muenchau
Assignee
Gilead Sciences
CA, US
IPC
A61K 31/70
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