The syringe system of the present invention includes a first or primary syringe barrel having a substantially closed end defining a delivery passage and an opposite open end. A removable closure seals the delivery passage of the first syringe barrel so as to define a container for containing a medical solution. A plurality of longitudinal channels are positioned on the inner surface of an enlarged diameter venting portion of the syringe barrel at the open end. A reciprocable stopper is provided for sealing the open end of the barrel so that the reciprocable stopper has a first position abutting the channels of the inner surface of the barrel so as to allow the medical solution to be lyophilized through the channels. The reciprocable stopper can then be longitudinally moved to a second position in the barrel in the in the direction of the delivery passage and beyond the channels to seal the lyophilized drug within the barrel.