05770388 is referenced by 89 patents and cites 23 patents.

Methods are disclosed for separating a component of interest from a mixture containing the component of interest and other components. The method comprises contacting a first liquid medium containing the component of interest and other components with a second liquid medium that is of different density than and/or of different viscosity than the first liquid medium. The contact is carried out in such a way that mixing of the media is minimized or avoided. The component of interest is bound to magnetic particles. The contacted first liquid medium and second liquid medium are subjected to a magnetic field gradient to allow the magnetic particles to migrate into the second liquid medium and separation of the component of interest from other components is realized. Also disclosed are assays employing the present method. Kits for carrying out the present method and assays are also disclosed.

Title
Method of separation employing magnetic particles and second medium
Application Number
455550
Publication Number
5770388
Application Date
December 13, 1993
Publication Date
June 23, 1998
Inventor
John Vorpahl
Livermore
CA, US
Agent
Theodore J Leitereg
Jerome Rosenstock
Leland K Jordan
Assignee
Dade Behring Marburg
IL, US
IPC
G01N 33/53
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