05756535 is referenced by 3 patents and cites 5 patents.

Substituted thiophenylalkenylcarboxylic acid guanidides, processes for their preparation, their use as a medicament or diagnostic, and a medicament containing them.

There are described substituted thiophenylalkenylcarboxylic acid guanidides of the formula I ##STR1## in which R(1) to R(5) have the meanings given in the claims, which are outstandingly active antiarrhythmic pharmaceuticals having a cardioprotective component and are outstandingly suitable for infarct prophylaxis and infarct treatment and also for the treatment of angina pectoris, where they also inhibit or greatly reduce the pathophysiological processes in the formation of ischemically induced damage, in particular in the initiation of ischemically induced cardiac arrhythmias, in a preventive manner.

Title
Substituted thiophenylalkenylcarboxylic acid guanidines, processes for their preparation, their use as a medicament or diagnositc, and a medicament containing them
Application Number
8/798259
Publication Number
5756535
Application Date
February 11, 1997
Publication Date
May 26, 1998
Inventor
Wolfgang Scholz
Eschborn
DE
Udo Albus
Florstadt
DE
Andreas Weichert
Egelsbach
DE
Hans Jochen Lang
Hofheim
DE
Heinz Werner Kleemann
Bischofsheim
DE
Joachim Brendel
Bad Vilbel
DE
Jan Robert Schwark
Frankfurt
DE
Agent
Finnnegan Henderson Farabow Garrett & Dunner L
Assignee
Hoechst Aktiengesellschaft
DE
IPC
C07D 333/32
A61K 31/38
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