05755753 is referenced by 554 patents and cites 25 patents.

A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A porous membrane is adapted to receive an electrolytic solution and become inflated to substantially conform a contacting exterior surface of the membrane to a skin layer. The membrane includes a cooling lumen for receiving cooling fluid. One or more thermal electrodes is positioned in the membrane and transfers thermal energy to the electrolytic solution. The electrolytic solution and cooling fluid creates a reverse thermal gradient from the skin surface to the underlying collagen tissue. A thermal power source is coupled to the thermal electrodes, and a source of electrolytic solution is coupled to the membrane.

Title
Method for controlled contraction of collagen tissue
Application Number
8/435822
Publication Number
5755753
Application Date
May 5, 1995
Publication Date
May 26, 1998
Inventor
Edward W Knowlton
Danville
CA, US
Agent
Wilson Sonsini Goodrich & Rosati
Assignee
Thermage
CA, US
IPC
A61F 7/000
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