05750349 is referenced by 120 patents.

According to this invention, antibodies which are useful and novel in that they have binding specificity to .beta.-amyloids or derivatives thereof, namely recognize the N-terminal, the C-terminal or central portions of the .beta.-amyloids, respectively, were obtained. By combining these antibodies, determination methods by which the .beta.-amyloids could be determined sensitively and specifically are provided. These determination methods are useful for diagnosis of diseases to which the .beta.-amyloids or their derivatives are related (for example, Alzheimer's disease), and the antibodies of this invention are useful for the development of preventive-therapeutic compositions for Alzheimer's disease.

Title
Antibodies to .beta.-amyloids or their derivatives and use thereof
Application Number
8/302808
Publication Number
5750349
Application Date
September 15, 1994
Publication Date
May 12, 1998
Inventor
Chieko Kitada
Osaka
JP
Asano Odaka
Ibaraki
JP
Nobuhiro Suzuki
Ibaraki
JP
Agent
David S Dike Bronstein Roberts & Cushman Resnick
David G Conlin
Assignee
Takeda Chemical
JP
IPC
G01N 33/53
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