05747060 is referenced by 183 patents and cites 35 patents.

A formulation for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible nerve blockade when implanted or injected in a patient, and an amount of colchicine effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without colchicine.

Title
Prolonged local anesthesia with colchicine
Application Number
8/622058
Publication Number
5747060
Application Date
March 26, 1996
Publication Date
May 5, 1998
Inventor
Mark Chasin
Manalapan
NJ, US
Paul Goldenheim
Wilton
CT, US
Richard Sackler
Greenwich
CT, US
Agent
Steinberg Raskin & Davidson P C
Assignee
Euro Celtique
LU
IPC
A61K 9/20
View Original Source