A method and system for testing the interoperability of application programs. The interoperability testing system uses an application-independent test script and application-specific command scripts to test the interoperability of application programs. An application-independent test script contains a series of high-level application-independent commands that are to be performed to test the application programs. Each application program to be tested has a corresponding application-specific command script. An application-specific command script contains an implementation of each high-level command for the corresponding application program. To test application programs, the interoperability testing system executes an application-independent test script by reading each high-level command from the test script, retrieving the implementation of that high-level command for the application program that is to perform that command, and executing that implementation.