05727548 is referenced by 444 patents and cites 43 patents.

A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; a first conductor and a second conductor each extend along the support and comprise means for connection to the circuitry. An active electrode, positioned to contact the liquid mixture and the first conductor, comprises a single layer deposit of an enzyme capable of catalyzing a reaction involving the compound, a conductive material, and an electron mediator, capable of transferring electrons between the enzyme-catalyzed reaction and the first conductor. A reference electrode is positioned to contact the mixture and the second conductor. The system includes circuitry adapted to provide an electrical signal representative of the current. The two-electrode strip is manufactured, e.g., by screen printing, an admixture of an enzyme a conductive material, and a mediator as a single layer onto the substrate.

Title
Strip electrode with screen printing
Application Number
590864
Publication Number
5727548
Application Date
June 6, 1995
Publication Date
March 17, 1998
Inventor
Graham Davis
Plainsborough
NJ, US
James Michael McCann
Oxford
GB
Irving John Higgins
Bedford
GB
Hugh Allen Oliver Hill
Oxford
GB
Agent
Fish & Richardson P C
Assignee
MediSense
MA, US
IPC
A61B 5/00
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