05722984 is referenced by 198 patents and cites 2 patents.

Disclosed is a coating material which has both antithrombogenic properties and contains an embedded radioisotope that makes the coating material radioactive As phosphorous 32 is emerging as the preferred isotope for vascular radioisotope stents, and phosphorylcholine has shown promise as an antithrombogenic stent coating, it is envisioned here to produce a stent with a phosphorylcholine coating with some of the phosphorous in the coating being phosphorous 32 rather than the naturally occurring, non-radioactive element phosphorous 31. In this manner one has a stent which has a single stent coating which is both antithrombogenic and radioactive. The stent could also utilize an inner layer which is both antithrombogenic and radioactive and an outer layer which is only antithrombogenic. A preferred embodiment of the invention is to produce a phosphorylcholine coated stent where some of the phosphate groups contain the radioisotope phosphorous 32.

Title
Antithrombogenic radioactive coating for an intravascular stent
Application Number
8/585760
Publication Number
5722984
Application Date
January 16, 1996
Publication Date
March 3, 1998
Inventor
Tim A Fischell
Nashville
TN, US
David R Fischell
Fair Haven
NJ, US
Assignee
Iso Stent
CA, US
IPC
A61N 5/00
A61B 17/00
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