A self-retaining catheter assembly is provided which includes a first and second catheter and a retaining sleeve. The first and second catheters each have an exterior surface and an interior surface defining a lumen which extends longitudinally through the catheter. The first catheter has a proximal portion which is for placement within a first subcutaneous area, and the second catheter has a proximal portion which is for placement within a second subcutaneous area. The first and second catheters also each have distal portions for placement within an area to be catheterized. The retaining sleeve is positioned around a portion of the exterior surfaces of the catheters which is located proximal to the distal portions of the catheters. The portions of the exterior surfaces of the catheters within the retaining sleeve are in a juxtaposed relationship and the retaining sleeve is positioned such that when the distal portions of the first and second catheters are within the area to be catheterized, the retaining sleeve is outside the area to be catheterized and distal to the first and second subcutaneous areas, and the assembly is secured in place.