05710630 is referenced by 338 patents and cites 9 patents.

A method for the analytical determination of the glucose concentration in a biological sample. In a detection step, light is irradiated into the sample and the light emerging therefrom after interaction with the sample emerges therefrom is detected in order to measure a physical light property affected by said interaction. The glucose concentration is determined from this measurement in an evaluation step. To provide a method for determining glucose in reagent-free and non-invasive manner, the invention proposes that a portion of the light emitted by the light source be guided along a reference light path of defined optical path length to the photodetector, that the total measuring light path also has a defined optical length and that the measuring light path after it has traversed the sample is so combined with the reference light path that the measuring light and the reference light interfere with each other. The photodetector measures an interference signal used in the evaluation step to determine the glucose concentration.

Title
Method and apparatus for determining glucose concentration in a biological sample
Application Number
8/530241
Publication Number
5710630
Application Date
October 10, 1995
Publication Date
January 20, 1998
Inventor
Dirk Boecker
Heidelberg
DE
Alexander Knuettel
Weinheim
DE
Matthias Essenpreis
Gauting
DE
Agent
Nikaido Marmelstein Murray & Oram
Assignee
Boehringer Mannheim
DE
IPC
G01B 9/02
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